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The link between UPS impairment and PD pathogenesis is increasingly clear because in addition to α-synuclein, Lewy bodies also contain ubiquitin, parkin and other proteasomal proteins [355-357] (Fig

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If you give the fluoroquinolone to a patient that already has damage done due to genetic reason, well, they’re just going to get wiped out because they already have an issue with that